Some of the recent and new update from WHO CNS tumor 20161) For astrocytic and oligodendroglial tumor IDH immunohistochemistry is must now2) New entity diffuse midline glioma,H3 K 27M mutant is added3) New variants of glioblastoma are giant cell and epitheloid glioblastoma4) New entity added in ependymoma is RELA fusion positive ependymoma5) Mesulloblastoma is classified into 4 classes based on WNT and SHH activated pathway#NimhansCNSupdate